Marie Claire Marie Claire
  • Celebrity
  • Fashion
  • Beauty
  • Culture
  • Power
  • Nice Talk
  • Fashion Month
  • More
    • Politics
    • Career Money
    • Health Fitness
    • Power Play
    • Travel
    • Promo Codes
    • Food Cocktails
    • About Us
    • Subscribe
    • Sex Love
  • Newsletter SIGN UP TO OUR NEWSLETTER
  • Marie Claire
    Marie Claire Newsletter

    Celebrity news, beauty, fashion advice, and fascinating features, delivered straight to your inbox!


    By submitting your information you agree to the Terms Conditions and Privacy Policy and are aged 16 or over.

    You are now subscribed

    Your newsletter sign-up was successful


    Want to add more newsletters?

    Marie Claire Daily

    Delivered daily

    Marie Claire Daily

    Get exclusive access to fashion and beauty trends, hot-off-the-press celebrity news, and more.

    Marie Claire Self Checkout

    Sent weekly on Saturday

    Marie Claire Self Checkout

    Exclusive access to expert shopping and styling advice from Nikki Ogunnaike, Marie Claire's editor-in-chief.

    Maire Claire Face Forward

    Once a week

    Maire Claire Face Forward

    Insider tips and recommendations for skin, hair, makeup, nails and more from Hannah Baxter, Marie Claire's beauty director.

    Livingetc

    Once a week

    Livingetc

    Your shortcut to the now and the next in contemporary home decoration, from designing a fashion-forward kitchen to decoding color schemes, and the latest interiors trends.

    Homes amp; Gardens

    Delivered Daily

    Homes Gardens

    The ultimate interior design resource from the world's leading experts - discover inspiring decorating ideas, color scheming know-how, garden inspiration and shopping expertise.


    An account already exists for this email address, please log in.
    Trending
    • NYFW
    • Life In Plastic
    • Cari Champion
    • New Books
    • Postpartum Psychosis
    1. Beauty
    2. Skincare

    The Newest FDA-Approved Injectable, SKINVIVE by JUVÉDERM, Is Unlike Anything on the Market

    “This is an important, watershed moment in injectable filler development.”

    Samantha Holender#039;s avatar
    By Samantha Holender
    Published 18 May 2023 In News

    When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works.

    skinvive injection
    (Image credit: Getty)
    Jump to category:
    • What It Is
    • How It Works
    • Who It's For
    • Side Effects
    • Results
    • Availability
    • Facebook
    • X
    • Pinterest
    Share this article
    Join the conversation
    Follow us
    Add us as a preferred source on Google
    Subscribe to our newsletter

    Step into a dermatologist’s office and the cosmetic world is your oyster. There are five FDA-approved neuromodulators at your disposal, RF microneedling machines, ablative lasers, chemical peels, and fillers galore. As of this week, doctors are going to have one more tool in their kit: SKINVIVE, which is unlike anything currently on the market. The micro droplet, hyaluronic acid injection, which was just approved by the FDA, is intent on smoothing out the skin and providing hydration, specifically on the cheeks. 

    “Oftentimes, new fillers are really just competitors for an existing class of fillers. SKINVIVE is actually the first in a new class of fillers, and we haven’t had that happen in a very, very long time,” says Dr. Macrene Alexiades, M.D. Ph.D. PLLC, dermatologist, founder of MACRENE Actives, and SKINVIVE by JUVEDERM clinical trial investigator. “It functions in a novel way that replaces or allows us to have an injectable alternative to what we would historically treat with either skin topicals, peels, or lasers.”

    The injection will cost you about the same as a traditional filler, lasts approximately six months, and requires less downtime than other treatments that offer comparable results. To read up on the glow-boosting, skin-smoothing injection ahead of its upcoming rollout, scroll ahead. 

    Latest Videos FromMarie Claire
    Watch full video here:

    skinvive before and after

    (Image credit: Getty)

    What Is It?

    Traditional fillers, like Juvederm, Radiesse, or Sculptra (to name a few), add volume to the skin. They can help reshape, define, or soften areas of the face by stretching the skin. While filler in the hands of a skilled professional has the potential to look natural, you do run the risk of filler migration or looking a little distorted. SKINVIVE, on the other hand, is entirely different. “It’s targeted directly into the dermis to increase hydration and improve skin quality and smoothness,” says Dr. Alexiades. “It’s not volumizing or stretching; it’s actually smoothing the skin as a direct outcome of the injection.” 

    How Does It Work?

    Once the hyaluronic acid gets injected into the skin, it disperses into a thin layer across the dermis. “It will literally diffuse, unlike other fillers which will sit in the position in which they’ve been implanted,” explains Dr. Alexiades. “It is really able to create an even dispersion. Of all the fillers in our history, this one is the least dependent on the artistic talent of the user.” 

    You may like
    • a white woman with glowing skin on a pink cream background next to a white jar of cream with gold writing, a pink tube of serum, and an amber jar with a white label TikTok Claims Volufiline Is Filler In a Bottle—Beauty Experts Weigh In on the Plumping Claims
    • A woman wearing glasses with her hair pulled back, smiling at the camera. She is next to 2 tubes of lip balm. I’m Ditching My Lip Filler Appointment for This Needle-Free Plumping Treatment
    • red background with dr diamond metacine products in cream packaging with red writing PSA: You Can Reverse Your Lip Age—Without Filler

    As soon as the SKINVIVE, which has a water-like texture, is in the skin, it gets to work boosting hydration. Hyaluronic acid is a humectant by nature, so it attracts water molecules and creates a healthy, plumped, glowing appearance. “We're putting back the hyaluronic acid mechanically as opposed to doing a fractionated resurfacing or an RF microneedling to induce hyaluronic acid.” 

    Am I a Candidate?

    If you’re on a mission to improve your skin texture, this is for you. SKINVIVE isn’t going to be the solution for deep set wrinkles, but it’s perfectly suited to improve skin quality, particularly if you have very fine lines along the cheeks. “This would be your top choice, there’s no other filler you would use,” says Dr. Alexiades. “You would never go back to stretching the skin to create smoothness.” 

    Marie Claire Newsletter

    Celebrity news, beauty, fashion advice, and fascinating features, delivered straight to your inbox!

    By submitting your information you agree to the Terms Conditions and Privacy Policy and are aged 16 or over.

    Are There Side Effects and Risks?

    As holds true with all fillers, the biggest risk is going to be vascular occlusion and necrosis. However that is rare (just make sure you’re going to a board-certified dermatologist). More common side effects are pretty short-term and are to be expected. You’re looking at subtle bruising or irritation, but nothing that should interfere with your daily life. Just avoid strenuous exercise or exposure to sun, heat, and alcohol in the first 24 hours. 

    When Will I See Results?

    “The nice thing about injecting this filler directly into the dermis is that you get an immediate result,” says Dr. Alexiades. “You start to get the hydration aspect immediately, which the skin is hungry for as hyaluronic acid diminishes with age.” Full results, however, will be visible at the 30-day mark. 

    When Can I Get It?

    SKINVIVE is hosting mandatory training for providers and anticipates a “slow rollout,” with the product being widely available within the next six months. 

    Samantha Holender
    Samantha Holender
    Social Links Navigation
    Senior Beauty Editor

    Samantha Holender is the Senior Beauty Editor at Marie Claire, where she reports on the best new launches, dives into the science behind skincare, and shares the breakdown on the latest and greatest trends in the beauty space. She's studied up on every ingredient you'll find on INCI list and is constantly in search of the world's glowiest makeup products. She's constantly tracking the biggest nail and hair trends to pop up in the beauty space, going backstage during fashion weeks, tracking celebrity looks, and constantly talking to celebrity hair stylists, nail artists, and makeup artists. Prior to joining the team, she worked as Us Weekly’s Beauty and Style Editor, where she stayed on the pulse of pop culture and broke down celebrity beauty routines, hair transformations, and red carpet looks. Her words have also appeared on Popsugar, Makeup.com, Skincare.com, Delish.com, and Philadelphia Wedding. Samantha also serves as a board member for the American Society of Magazine Editors (ASME). She first joined the organization in 2018, when she worked as an editorial intern at Food Network Magazine and Pioneer Woman Magazine. Samantha has a degree in Journalism and Mass Communications from The George Washington University’s School of Media and Public Affairs. While at GWU, she was a founding member of the school’s HerCampus chapter and served as its President for four years. When she’s not deep in the beauty closet or swatching eyeshadows, you can find her obsessing over Real Housewives and all things Bravo. Keep up with her on Instagram @samholender.

    Read more
    A woman wearing glasses with her hair pulled back, smiling at the camera. She is next to 2 tubes of lip balm.
    Makeup I’m Ditching My Lip Filler Appointment for This Needle-Free Plumping Treatment New holy grail alert.
    By Ariel Wilson
    red background with dr diamond metacine products in cream packaging with red writing
    Skincare PSA: You Can Reverse Your Lip Age—Without Filler Volume loss and lip lines have officially met their match.
    By Samantha Holender
     
     
    ocean water with new ultra violette spf and two women wearing sunscreen
    Skincare PSA: You Can Buy SPF With the New FDA-Approved Filter as of Today Ultra Violette’s Unblock Screen contains Bemotrizinol, the first new filter in the US market in 27 years.
    By Samantha Holender
    Rodan + Fields
    Skincare This New Serum Will Trump All the Other Serums in Your Lineup, According to Derms and Editors Sponsored by Rodan + Fields Your trusted source for effective skincare.
    By Aniyah Morinia
     
     
    Latest in Skincare
    a woman outside with long blonde wavy hair next to yellow sunflowers and a bunch of skincare products
    Skincare I Won’t Gatekeep—5 Incredible Skincare Brands You’ve Never Heard Of
    a mature woman framed out next to products to firm loose or sagging skin
    Skincare I Polled Derms to See if This Viral Serum Will Actually Firm Sagging Skin
     
     
    Rodan + Fields
    Skincare This New Serum Will Trump All the Other Serums in Your Lineup, According to Derms and Editors
    A woman with glowing skin and a slicked back bun next to a therabody cryotherapy tool.
    Skincare This $18 Cryo Tool Instantly Depuffs My Face
     
     
    Latest in News
    A split image of Zizi Strallen in costume as Mary Poppins and Princess Kate and Princess Charlotte with their heads together at the Commonwealth Games
    Royals Princess Charlotte Had a Special Backstage Experience Orchestrated by Mom Kate
    collage of New York Fashion Week guests and celebrities wearing the statement skirt trend
    Fall fashion New York Fashion Week's Easiest Outfit Formula Starts With a Statement Skirt
     
     
    Prince Harry looks at Prince William on the Buckingham Palace balcony as both wear military uniforms
    Royals Prince William's Stance on Prince Harry Has Changed to a "Cold War"
    collage of the best celebrity looks at the 2026 Toronto Film Festival
    Celebrity Style TIFF 2026's Best-Dressed Stars Are Bringing Their Fashion A-Game to Toronto
     
     
     
     
     
     
     
     
    Marie Claire
    RSS
    • About us
    • Contact Future's experts
    • Contact us
    • Advertise Online
    • Newsletter
    • Terms and conditions
    • Privacy policy
    • Cookies policy
    • Careers
    Add as a preferred source on Google Add as a preferred source on Google

    Marie Claire is part of Future US Inc, an international media group and leading digital publisher. Visit our corporate site.

    © Future US, Inc. Full 7th Floor, 130 West 42nd Street, New York, NY 10036.